Book easy, cheap flights from Guatemala to Panama with Copa Airlines, punctuality leader in Latin America.

Cheap Flights from Guatemala City (GUA) to Panama City (PTY) start at $207 for one-way and $271 for round trip. Earn your airline miles on top of our rewards!

Vuelos baratos de Guatemala a Panamá desde USD307 con Copa Airlines, lider en puntualidad en América Latina

Find the best deals on flights from Guatemala City (GUA) to Panama City Tocumen International (PTY). Compare prices from hundreds of major travel agents and airlines, all in one search.

Each day, there are between 4 and 5 nonstop flights that take off from Guatemala City and land in Panama City, with an average flight time of 2h 26m. The most common departure time is 4:00 pm and most flights take off in the afternoon.

Compare cheap Guatemala to Panama flight deals from over 1,000 providers. Then choose the cheapest plane tickets or fastest journeys. Flight tickets to Panama start from $116 one-way.

There are 7 ways to get from Guatemala to Panama by plane, bus, car, or shuttle. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Find flights to Panama from $144. Fly from Guatemala on Copa Airlines, Avianca, United Airlines and more. Search for Panama flights on KAYAK now to find the best deal.

There are 7 ways to get from Guatemala to Panama City by plane, shuttle, bus, or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Compare cheap Guatemala City to Panama flight deals from over 1,000 providers. Then choose the cheapest plane tickets or fastest journeys. Flight tickets to Panama start from $143 one-way.