Butovsky believes xenon has potential as an AD treatment. A Phase 1 clinical trial of xenon at BWH is recruiting healthy elderly volunteers to test safety and effects on immune cells. “I hope this ...

Atlas Overview. A survey of regulatory RNA used two cohorts (A), six brain regions (B), and four AD traits (D) to examine four types of RNA (C), turning up more than 25,000 differences between AD and ...

Some drugs can activate AMPK, most prominently metformin, which is approved for diabetes and being trialed in dementia. Less well-known is aldometanib, developed by Lin’s team, which blocks aldolase, ...

Barbara Lazarus’ two sons, David and Daniel, were healthy and active kids, but things changed in their early 20s. David developed severe psychiatric symptoms, which were diagnosed as schizoaffective ...

HSV-1 is a common virus. During infection, its DNA incorporates into host chromosomes, where it lies dormant. An estimated two-thirds of adults worldwide carry these latent HSV-1 genes. Previous work ...

This letter was prompted by your recent perspective paper and the responses it provoked in an Alzforum discussion. Generally, my comments are offered with the intellectual humility required when ...

I thank you for your response, for its thoughtfulness and thoroughness. The first round of a debate is most useful for isolating the crux. I therefore kindly ask for one more public round. This would ...

I thank you for your response, for its thoughtfulness and thoroughness. The first round of a debate is most useful for isolating the crux. I therefore kindly ask for one more public round. This would ...

Some people’s brains age faster than average, some slower. Scientists quantify this “brain age gap” by subtracting a person’s chronological age from their brain’s biological age. Because aging brains ...