San Francisco (6-10) rides a three-game losing streak into a matchup with (-) on Sunday, January 5, 2025 at State Farm ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

The San Francisco 49ers entered their Week 18 finale on the road against the Arizona Cardinals with several starters ruled ...

The Arizona Cardinals did not have second-year receiver Michael Wilson. After suffering a hamstring injury Friday, making him ...

The Arizona Cardinals face the San Francisco 49ers in Week 18 at State Farm Stadium to close out the season. They want to ...

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The Arizona Cardinals face the San Francisco 49ers in their season finale and have made roster moves to prepare for the game ...

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After the two Week 18 games on Saturday and eight kicking off at 1 p.m. ET, five more are set to begin at 4:25 p.m. ET and ...

Niners Wire’s Kyle Madson takes Cardinals fans behind enemy lines before the Cardinals and 49ers play in Week 18.

Week 18 in the NFL began Saturday with two games. Another eight kick off at 1 p.m. ET on Sunday. Some playoff spots are up ...