Winning your fantasy football matchups in Week 3 will mean making the right choices on these tough position calls.

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian McCaffrey and Deebo Samuel.

Head coach Kyle Shanahan confirmed that Talanoa Hufanga is set to make his 2024 season debut when the San Francisco 49ers ...

San Francisco 49ers defensive coordinator Nick Sorensen, offensive line/run game coordinator Chris Foerster, and quarterback ...

The San Francisco 49ers face the Los Angeles Rams in their first divisional matchup. The 49ers are coming off a loss to the ...

Injuries already are accruing across the NFL, knocking several star players out and forcing teams to turn to backups and ...

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

Sam LaPorta hopes to shake his slow start, Dalton Kincaid fights for looks in the Bills’ remade skill corps, and Hunter Henry ...