James Conner ran for 110 yards and two touchdowns, offensive lineman Jonah Williams added the first score of his NFL career and the Arizona Cardinals used a stellar defensive performance to beat the New England Patriots 30-17.

With a weaker opponent in the building after three straight difficult matchups, the Cardinals' run game once again shone. James Conner finished with 110 yards on 16 carries and Murray added 11 yards on five attempts. The Cardinals averaged 5.1 yards per carry and finished with 163 rushing yards, their most since Week 9.

Conner can move into fifth place in the Cardinals’ all-time in career rushing list with a decent game against the Patriots.