Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

CAMBRIDGE, Massachusetts, Jan. 13, 2025 (GLOBE NEWSWIRE) -- ProMIS Neurosciences Inc. (Nasdaq: PMN) (ProMIS), a clinical-stage biotechnology company focused on the generation and development of ...

Artificial insemination is commonly used in animal production and usually involves the dilution and preservation of semen (Prapaiwan et al., 2016). The main temperature for preservation is 17 °C ...

One advantage of slow footprinting is that usually no special apparatus (e.g., laser, synchrotron ... in structure often provides an answer. For amyloid proteins, structures of the starting state ...

While there has been extensive research on the characterization and analysis of nanoparticles, particularly focusing on their optical properties, the quantification of monomer–dimer distributions ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

Salk Institute researchers have identified a key protein that may help users of GLP-1 drugs such as Ozempic and Wegovy ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...

Protein is kind of the It Girl of nutrients right now. It's the macro that's good at everything: building muscle, supporting immune function, sustaining energy levels, shoring up bone health, and ...