scienceopen.com24d
Structure and dynamics of the interaction of Delta and Omicron BA.1 SARS-CoV-2 variants with REGN10987 Fab reveal mechanism of antibody action
Interaction of REGN10987 with Wuhan, Delta, Omicron BA.1, and mutated variants of RBDs is analyzed by microscale thermophoresis, molecular dynamics simulations, and ΔG calculations with umbrella ...
Frontiers26d
Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments
Furthermore, we introduce microscale thermophoresis (MST) as a tool to characterize protein-small molecule interactions in biological liquids. Notably, the results of MST assays indicate that ERK1 and ...