ATP is the primary energy currency in cells. It consists of an adenine base, a ribose sugar, and three phosphate groups. The hydrolysis of ATP releases energy that is used to drive various cellular ...
The conserved head structure, the membrane portion and the peripheral stalk (or stalks) together could have formed a translocase that coupled ATP hydrolysis to the transfer of RNA and/or proteins ...
J-domain proteins (JDPs) coevolved with Hsp70s to trigger ATP hydrolysis and catalytically upload various substrate polypeptides in need to be structurally modified by the chaperone. Here, we measured ...
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