Around 1.5 million patients succumb to the disease caused by the bacterium Mycobacterium tuberculosis (Mtb). The novel ...

tuberculosis often manifests as extrapulmonary or disseminated disease Screen patients for risk factors for Mycobacterium tuberculosis and test them for infection before initiating ...

In contrast to pulmonary tuberculosis, which is not a diagnostic challenge, disseminated disease without typical miliary pattern on plain chest x-ray or extrapulmonary tuberculosis without ...

In extrapulmonary TB or cases where pulmonary TB diagnosis remains uncertain, biopsy and histopathological examination of affected tissues may be necessary. Histopathology can reveal granulomas ...

Different types of immune cells form, so-called granulomas, in which M. tuberculosis can survive for years (latent infection). They fall into a permanently inactive state with reduced metabolic ...