As described in their paper published in Volume 15 of Scientific Reports on January 2, 2025, the research team employed molecular docking analysis to screen a diverse library of natural compounds ...

The compound contains a berkelium atom “sandwiched between two cyclic carbon molecules ... allows us to study the fundamental electronic structure and bonding.” Berkelium is one of the ...

Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon 97331, United States Laboratory of Medicinal Chemistry, Kyoto Pharmaceutical University, Kyoto ...

In this study, the authors first used an AlphaScreen assay to identify a series of tryptophan-based cyclic peptide compounds with ... peptide's size and side chain structure, they identified ...

Scientists have coaxed one of the universe’s most stubborn elements into a new compound. Formed under intense pressures, the newly discovered compound packs helium atoms into crystalline iron ...

To assess the risk of chance correlations, we conducted a y-scrambling validation by randomly permuting the cyclic peptides’ permeability labels (Y-values) across the dataset. Following the identical ...

Tetrapeptides with alternating cationic and aromatic residues such as SS-31 (elamipretide) show promise as therapeutic compounds for mitochondrial disorders. In this study, we conducted a quantitative ...