Muscarinic acetylcholine receptors (mAChRs) are a type of receptor in the brain that respond to the neurotransmitter acetylcholine. They play a crucial role in various brain functions, including ...

A pathway once considered fundamental in Alzheimer’s disease is being studied intensely again, and may soon result in safer, ...

A study by the (UPV/EHU) demonstrates that the drug WIN55,212-2 protects the brain and reverses early cognitive damage caused ...

Research highlights the potential of deep learning in creating proteins that neutralize snake venom, offering new solutions ...

As per the Brain and Behavior Research Foundation, it combines two compounds called xanomeline and trospium chloride. This is ...

M2 receptors, located on the postganglion endings of the cholinergic fibers, with the role of limiting further acetylcholine release from the postganglion endings; and M3 receptors, located on the ...

ZYN, the popular brand of flavored nicotine pouches, recently earned FDA authorization for reducing smoking, but some ...

Muscarinic receptors are involved with neurotransmission via acetylcholine and glutamate, and are hypothesised to be dysfunctional in schizophrenia. Most drugs developed to treat schizophrenia to ...

Ekbom's syndrome has become de rigeur as a subject of consequence for neurologists following the demonstration that dopamine receptor agonists may be remarkably effective Some classic neurological ...

The FDA approved a wide range of therapies in 2024, including many new molecular entities and biological products.

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Achieve Life Sciences, Inc., a late-stage pharmaceutical company focused on the global development and commercialization of ...