Vaccine Step Down. A person’s probability of developing dementia over seven years increased with age. It was higher in the ...

A new consortium aims to speed the pace of basic science discovery in AD and related diseases. A future AI assistant is to ...

See α-Synuclein. Candidate tracer SY08 detects α-synuclein deposits in the brainstem (right) and parietal cortex (left) of people with Parkinson’s (middle) and dementia with Lewy bodies (bottom), but ...

First author Hamilton Oh, now at Icahn School of Medicine at Mt. Sinai, New York, and colleagues identified these potential markers during a proteomics analysis of CSF from 3,397 participants in six ...

The scientists concluded that while the two markers perform similarly, they yield complementary information, and sequential ...

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I am consultant for Janssen pharmaceutica, Remynd NV, Eisai and other companies ...

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TgF344-AD rats express human APP with the Swedish mutation and human PSEN1 with the Δ exon 9 mutation. Both transgenes are driven by the mouse prion promoter (Cohen et al., 2013). Compared with levels ...

Tau hyperphosphorylation and conformational changes in the brain parenchyma start around seven months. Tangle-like pathology is mainly observed in the brain stem and spinal cord, and to a lesser ...