The bruised and battered San Francisco 49ers will need these five players to step up against the short-handed Los Angeles ...

Aiyuk missed most of training camp due to a hold out, so a slow start isn't a huge surprise. Now, in Week 3, he should be up to speed and he gets a defense that has been pretty awful so far. The Rams ...

Herbert injured his right leg in the third quarter of Week 2’s 26-3 win against the Carolina Panthers trying to escape the ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

Are Joe Burrow and Ja'Marr Chase about to go off for the Bengals? What should we expect from Colts QB Anthony Richardson? Michelle Magdziuk and Matt Okada predict whether 11 noteworthy players will go ...

With RB Christian McCaffrey (Achilles) on injured reserve, WR Deebo Samuel (calf) all but ruled out and TE George Kittle (hamstring) now uncertain, the 49ers are badly in need of players that can ...

Deebo Samuel, Cooper Kupp and Isiah Pacheco were just a few of the high-profile players who joined the likes of Christian McCaffrey and Puka Nacua among the list of notable significant injuries. And ...

The NFC North is one of only two divisions without a winless team through two weeks of the NFL season. Here are the latest On SI NFC North pow ...

Jamey Eisenberg believes injuries to key players have set the stage for a breakout performance by Brandon Aiyuk ...

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...