The Buffalo Bills (8-2) won their fifth straight game with a 30-20 victory over the Indianapolis Colts (4-6) at Lucas Oil ...

T he Indianapolis Colts are not favored in their matchup against the Buffalo Bills. Most people wouldn’t expect them to be.

Indianapolis Colts quarterback Joe Flacco turned the ball over four times on Sunday against the Buffalo Bills in a 30-20 loss.

Buffalo Bills running back James Cook flips into the end zone against the Indianapolis Colts for his eighth rushing touchdown of the season.

The Bills had not won in Indianapolis since 1998, losing their last six combined at the old RCA Dome and Lucas Oil Stadium.

Off-platform dime! Buffalo Bills quarterback Josh Allen's improv lob to wide receiver Mack Hollins goes for a 44-yard gain ...

He's certainly not first. Jayden Daniels is way ahead in that race. Bo Nix of the Denver Broncos has probably been better too ...

Buffalo Bills safety Taylor Rapp corrals Indianapolis Colts quarterback Joe Flacco's overthrown pass for the Bills' third interception of the day.

Taron Johnson returned Joe Flacco’s first pass 23 yards for a touchdown, and Josh Allen and James Cook each scored on TD runs ...

Indianapolis Colts quarterback Joe Flacco's struggles were on full display during a 30-20 loss to the Buffalo Bills on Sunday ...

The Buffalo Bills have locked up a fifth-straight win against the Indianapolis Colts in Week 10. The Bills (8-2) cruised for ...

The Buffalo Bills travel to Lucas Oil Stadium to face the Indianapolis Colts in Week 10, with the team aiming to reinforce ...