Watch the top highlights of San Francisco 49ers wide receiver Deebo Samuel Sr. from the 2024 NFL season. Watch the top ...

Watch the top highlights of San Francisco 49ers defensive lineman Nick Bosa from the 2024 NFL season. Watch the top ...

Former New York Jets head coach Robert Saleh has a contract offer from the San Francisco 49ers to become the NFL's ...

The San Francisco 49ers are promoting Klay Kubiak from offensive passing game specialist to offensive coordinator, head coach ...

The Detroit Lions meet the San Francisco 49ers on Monday Night ... LIVE UPDATES:Lions vs 49ers score today, highlights But the Lions and 49ers have gone completely separate ways this season ...

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

On top of the 49ers 40-34 loss to the Detroit Lions, San Francisco 49ers quarterback Brock Purdy re-injured his throwing elbow on Monday night. Related Articles San Francisco 49ers | Mother of ...

Jared Goff threw three touchdown passes as the Detroit Lions overpowered the San Francisco 49ers 40-34 in a high-scoring thriller on Monday Night Football. After the 49ers impressed in the first ...