Crucial to all life on Earth, the 15th element of phosphorus remains a real puzzle for astronomers. Specialized space telescopes are needed to shed light on the issue.

A study identifies the P2X7 receptor as a driver of post-traumatic epilepsy (PTE) following brain injuries. Blocking the receptor reduced brain hyperexcitability and damage in models.

The manuscript by Goyal et al report substrate-bound and substrate-free structures of a tripartite ATP independent periplasmic (TRAP ... I do not feel it is appropriate to model in a publicly ...

Challenging centuries-old assumptions about thermodynamics, a new study in published in Physical Review Letters has shown ...

"We used this substance as a prototype, a model based on which we could design novel versions of the molecule [with minor ... the parasite's energy mechanism (ATP) due to an increase in calcium ...

Most clinically used KIs act by blocking ATP binding site of active (type I ... potential CDK9 and CYP3A4 inhibitors by using a predictive QSAR model and in silico synthesis. Molecular docking studies ...

The human brain is a complex powerhouse, responsible for orchestrating thoughts, emotions, and memories. Its nerve cells ...

Using human tissue samples and multiple approaches in mouse models of renal failure ... Here, authors show that ATP-independent membrane protein chaperones can serve as a simple design platform ...

As the capabilities of generative AI models have grown, you've probably seen how they can transform simple text prompts into ...

This valuable work provides novel insights into the substrate binding mechanism of a tripartite ATP-independent periplasmic (TRAP) transporter, which may be helpful for the development of specific ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...