A study identifies the P2X7 receptor as a driver of post-traumatic epilepsy (PTE) following brain injuries. Blocking the receptor reduced brain hyperexcitability and damage in models.

Challenging centuries-old assumptions about thermodynamics, a new study in published in Physical Review Letters has shown ...

The human brain is a complex powerhouse, responsible for orchestrating thoughts, emotions, and memories. Its nerve cells ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

The protein was then synthesized and tested in the lab. It glowed—a clear sign of success. The AI had effectively charted a ...

That's the equivalent of 500 million years of evolution being processed by AI, the research team estimates, and it opens the ...

Multi-Modal Models: A multi-modal discovery approach was implemented that engineered-in potency against the novel target and engineered-out a specific off-target interaction. The NCE library displayed ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Chief R&D and commercial officer Najat Khan, PhD, tells GEN Edge company aims to improve design of studies, accelerate enrollment, and enhance evidence generation.

An artificial intelligence model has created a new protein that researchers say would have taken 500 million years to evolve ...

Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, ...