Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the ...

Stop the Spread. Injecting saline into mouse kidneys did not affect the left or right substantia nigra (top). Injecting fibrils of α-synuclein ablated about half of the dopaminergic neurons (middle ...

Data from the first 16 weeks of the open-label extension phase of the RewinD-LB trial are expected in 1Q 2025 and will include data from ...

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...

A compound that showed early promise in the treatment of Parkinson's disease in fruit flies has also shown neuroprotective ...

Amyloid plaques, tau tangles, and Lewy bodies frequently appear together ... may allow amyloid deposition to spread tangle pathology to the cortex. However, they observed that no direct causal ...

individuals with prodromal Lewy body disease or dementia with Lewy bodies; patients diagnosed with MCI or dementia who possess recent conclusive cerebrospinal fluid biomarker results, regardless ...