San Francisco 49ers running back Isaac Guerendo was forced to exit ... who stepped in for Guerendo, and fullback Kyle Juszczyk—the team was left thin at the position. "It was tough, especially ...

Isaac Guerendo was carted off the field with injuries to his left knee and ankle. The team ruled out his return today. Guerendo was injured on the team’s fourth play from scrimmage, only 1:55 into the ...

Isaac Guerendo was carted off the field with ... on a 2-yard run. Fullback Kyle Juszczyk played halfback the rest of the drive, which the 49ers capped with a 51-yard Jake Moody field goal.

Even for tight end George Kittle and fullback Kyle Juszczyk, both staples of the Kyle ... at the start of 2025 is rookie running back Isaac Guerendo. He suffered a left knee injury on the fourth ...

Less than two minutes into the game, running back Isaac Guerendo was carted off ... have their two longest-tenured players in fullback Kyle Juszczyk and tight end George Kittle, each of whom ...