This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

What is Cushing's syndrome? Cushing's syndrome is a hormonal disorder. It’s caused when you have high levels of the hormone cortisol over a long time. Cushing's syndrome is fairly rare. It most often ...

By Dr. Sanchari Sinha Dutta, Ph.D. Study uncovers how gradual CAG repeat expansion in neurons drives the onset of ...

Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated ...

Published in Cell, the study titled, “Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease,” ...

Huntington's disease is a hereditary neurodegenerative disorder caused by an autosomal dominant mutation. The hallmark symptom of Huntington's disease is the presence of progressive chorea ...

WASHINGTON — Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who inherit it ...

This microscope photo provided by the McLean Hospital's Harvard Brain Tissue Resource Center in January 2024 shows cells in the caudate nucleus structure of the brain in a person with Huntington's ...