This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time. The cause is related to expansion of repeating DNA units, in which ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the brain to ...

However, sparse disease-metabolite associations pose a challenge to current deep learning-based methods, limiting comprehensive feature learning. To address this, we propose a novel Weighted Graph ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...

Copyright 2025 The Associated Press. All Rights Reserved. This microscope photo provided by the McLean Hospital’s Harvard Brain Tissue Resource Center in January ...

Most clin­i­cal tri­als for Hunt­ing­ton’s dis­ease have run aground in the last few years, but aca­d­e­m­ic re­searchers haven’t been dis­suad­ed from try­ing to shift how … ...