eLife2d
mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance
This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...
Medscape3d
Early Signs of Huntington’s Detectable Decades Before Symptoms Present
Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...
Johns Hopkins Medicine5d
Cushing's Syndrome
What is Cushing's syndrome? Cushing's syndrome is a hormonal disorder. It’s caused when you have high levels of the hormone cortisol over a long time. Cushing's syndrome is fairly rare. It most often ...
News Medical5d
Decades of DNA expansion linked to Huntington’s disease neurodegeneration
A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...
Medscape6d
Huntington’s Disease: Do Beta Blockers Delay Motor-Symptom Onset and Progression?
Beta blockers were associated with later appearance of motor symptoms and slower symptom worsening, but an outside expert ...