Already riddled with injuries, Detroit lost three more defenders in Sunday's loss to the Bills. At what point is too much, too much?

After 11 consecutive victories, the Detroit Lions still found themselves in a position of needing to prove themselves. Against the Buffalo Bills, an AFC powerh ...

Josh Allen took a shotgun snap, moved up in the pocket and backed up, rolled left and threw right. It was just another play, ...

McNeill appeared to injure his knee while putting pressure on quarterback Josh Allen in the third quarter and landed ...

Several players from the Bills' locker room, including coach Sean McDermott, shared their thoughts on the Lions' early onside ...

The Detroit Lions lost a high-scoring battle with the Buffalo Bills 48-42 on Sunday and after the game, Dan Campbell took the ...

The Detroit Lions had their 11-game win streak snapped on Sunday in a 48-42 loss to the Buffalo Bills, and head coach Dan ...

Mike Payton discusses the Detroit Lions loss to the Buffalo Bills and how the blame falls on Dan Campbell.

The most thrilling matchup of the day took place in Detroit, where the Buffalo Bills outlasted the Lions in a 48-42 shootout, ...

The Detroit Lions ' injury-riddled defense took two more hits Sunday as starters Alim McNeill and Carlton Davis III suffered ...

The Lions defense gave up a season-high in yards and points after only forcing one Buffalo Bills punt in 10 possessions in ...

The Bills won a dazzling 48-42 shootout over the Lions Sunday night. Here's how Sal Maiorana graded their performance.