This manuscript reports the substrate-bound structure of SiaQM from F. nucleatum, which is the membrane component of a Neu5Ac-specific Tripartite ATP-dependent Periplasmic (TRAP) transporter. Until ...

However, nitrogenase also requires large amounts of biochemical fuel, in the form of energy-producing adenosine triphosphate (ATP ... FeSII relaxes its structure, leading to dissociation of ...

The Max Planck Institute of Molecular ... the structure and thus the activity of KEA3 changes according to the pH value. However, this only occurs when KEA3 has also bound ATP and NADPH.

--(BUSINESS WIRE)--Ensem Therapeutics, Inc. (ENSEM), a pioneering drug discovery and development company that leverages its unique Kinetic Ensemble ® platform to advance innovative small molecule ...

A new study identifies aldolase A as a critical node that, when inhibited in cancer cells, turns glycolysis into an ATP-consuming process. Targeting aldolase A to induce imbalanced glycolysis ...

The work highlights the utility of cryo-EM in studying small proteins and uncovering targets for structure-based drug ... Here, authors show that ATP-independent membrane protein chaperones ...

Can a protein involved in delivering Vitamin D to target tissues have an altered serum profile in psoriasis patients with ...

Agreements to drive clinical research, enhance product safety, and combat respiratory diseases KUALA LUMPUR, MALAYSIA / ACCESSWIRE / November 29, 2024 /NASDAQ-listed AGAPE ATP Corporation ("ATPC ...

(AP) During a press conference at the Brisbane International, he said, “We have problem there.We have a problem in the very - how can I say - structure of the ATP is that as players we only have ...

Tennis world rankings are calculated by the ATP, who award points based on a player's performance at particular tournaments. The further a player progresses in a sanctioned event, the more ...

French tennis star Gaël Monfils became the oldest ever player to claim an ATP Tour singles title when he won the ASB Classic in Auckland on Saturday, surpassing the previous record set by Roger ...

This valuable work provides novel insights into the substrate binding mechanism of a tripartite ATP-independent periplasmic (TRAP) transporter, which may be helpful for the development of specific ...