based on its R100 adeno-associated virus (AAV) transgene cassette. Unlike other virus-based vectors used for retinal diseases, R100 treats the entire retinal surface at low doses and does not ...

According to Dr Erik Wiklund, CEO of Circio, Norway: “Gene therapies have been available for more than 30 years, and there are now AAV-based and ... a genetic cassette that forms a circular ...

Sensing of AAV vector components in plasmacytoid DCs (pDCs ... Next to the viral capsid, also the cargo, i.e., the recombinant genome consisting of the transgene expression cassette flanked by the ...

Cassette Beasts, a new creature-collecting game, is now available on Android and is free to try. The game is published by respected publisher Raw Fury and offers premium features at a reasonable ...

Though CD sales remained constant, cassette tape sales have also been making a strong comeback as well. From 81,000 units in 2015 to 436,400 in 2022, the resurgence has been driven by Gen Z’s ...

For some people, cassettes are enjoying a tiny comeback. A few artists release albums on cassette as well as digitally and on CD and vinyl, but not many of these cassettes are heard because there are ...

Using this system, we demonstrate programmable insertion of a 1.1 kb gene expression cassette into specific genomic loci of human cell lines and primary T cells. Mechanistic studies reveal that CREATE ...

This important study reveals a new mechanism for gene regulation in neurons by an RNA binding protein called RBM20 previously studied in the heart. The methods used are compelling, including the ...