Stop the Spread. Injecting saline into mouse kidneys did not affect the left or right substantia nigra (top). Injecting fibrils of α-synuclein ablated about half of the dopaminergic neurons (middle ...

Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for ...

T he main neuropathological feature of Parkinson's disease is the loss of dopaminergic neurons in the substantia nigra pars compacta. Specifically, dopaminergic neurons in the ventral tier of the ...

Innovative treatment for Parkinson's disease: microscopic particles combined with light therapy offer a non-surgical solution ...

Parkinson's disease (PD) is the second most common neurodegenerative disorder, primarily characterized by motor dysfunction.

The substantia ... [+] nigra plays an important role in reward, addiction, and movement. Degeneration of this structure is characteristic of Parkinson's disease. In late 2018, Japanese ...

A nanoparticle-based wireless deep brain stimulation system has been shown to reverse Parkinson's disease in groundbreaking ...

A novel wireless photothermal DBS nanosystem uses nanoparticles to target and restore damaged neurons in Parkinson’s disease, ...

Researchers developed a wireless photothermal nanosystem using gold nanoshells to stimulate thermosensitive TRPV1 receptors ...

When they analysed the substantia nigra they recorded a rapid loss of Substance P (a ... Our work identifying that a silent stroke can lead to Parkinson’s disease shows it is more important than ever ...

A research team led by Prof. CHEN Chunying from the National Center for Nanoscience and Technology of the Chinese Academy of Sciences designed a wireless photothermal DBS nanosystem, Au@TRPV1@β-syn ...