Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists. The findings ...

Physical activity is not only important for fitness but also for overall health. This is confirmed by a new study, which ...

A third autotrophic pathway (Wood–Ljungdahl pathway) uses a reductive acetyl-CoA pathway and is only found in strictly anaerobic bacteria and archaea. A fourth pathway uses the 3 ...

or CO 2 to acetate via a unique metabolic pathway in which acetyl coenzyme A (acetyl-CoA) is an intermediate. However, even for acetogens, CO retards growth, so their tolerance to it needs to be ...

His team identified PanK4 as a key regulator of energy metabolism in skeletal muscle, regulating glucose uptake and fatty acid oxidation and being activated by physical exercise. The study suggests ...

Propionyl-CoA and butyryl-CoA levels increased in a dose-dependent manner, correlating with higher histone modifications, while acetyl-CoA levels remained unchanged with propionate but decreased ...