Peptide-centric approaches—sometimes referred to as shotgun strategies or bottom-up proteomics—are now widely adopted as a means of identifying proteins present in biological mixtures.

And that is becoming easier to achieve. Proteomics often uses a bottom-up approach with the LC-MS/MS technique, in which proteins are first separated by size with liquid chromatography (LC ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...