The newly engineered HAC is based on a synthetic repeated DNA sequence called the alphoid tetO dimer. One part of the ... by a tetracycline repressor (tetR) binding site (tetO), which can be ...

They engineered an adenoviral vector to include a repressor protein (TetR) and its binding site (tetracycline operator, TetO) in the MLP. Adding these two elements means that once the MLP is ...