Using α-syn fibril-induced PD model, researchers aimed to restore the degenerated dopaminergic neurons in the substantia nigra of the midbrain by the wireless DBS nanosystem. After stereotactic ...

A novel wireless photothermal DBS nanosystem uses nanoparticles to target and restore damaged neurons in Parkinson’s disease, ...

This results in ATP and ion homeostasis disturbances, which lead to selective death of the substantia nigra dopaminergic neurons. Well known as a Parkinson's disease model, the MPTP animal model ...

However, it now appears one of the lasting effects of a silent stroke can be the death of dopaminergic neurons in the substantia nigra in the brain, which is an important region for movement ...

This webinar will focus on generation of human midbrain organoids for the study of Parkinsons Disease. In order to simplify the workflow, an established method for 2-D differentiation of floor plate ...

Results suggest that the implanted neurons have survived transplantation ... producing cells in a part of their midbrain called the substantia nigra, which is responsible for motor control.