Parkinson's disease (PD) is the second most common neurodegenerative disorder, primarily characterized by motor dysfunction.

The main neuropathological feature of Parkinson's disease is the loss of dopaminergic ... tier of the substantia nigra pars compacta, known as the nigrosome. Imagine the midbrain as a bustling ...

A novel wireless photothermal DBS nanosystem uses nanoparticles to target and restore damaged neurons in Parkinson’s disease, ...

Researchers developed a wireless photothermal nanosystem using gold nanoshells to stimulate thermosensitive TRPV1 receptors ...

It receives inputs from the limbic system and the basal ganglia and sends outputs to midbrain areas that are involved in the release of dopamine (the substantia nigra pars compacta and ventral ...

A nanoparticle-based wireless deep brain stimulation system has been shown to reverse Parkinson's disease in groundbreaking ...

Results suggest that the implanted neurons have survived transplantation ... producing cells in a part of their midbrain called the substantia nigra, which is responsible for motor control.

A research team led by Prof. CHEN Chunying from the National Center for Nanoscience and Technology of the Chinese Academy of Sciences designed a wireless photothermal DBS nanosystem, Au@TRPV1@β-syn ...