The 49ers are targeting Week 15 for Dre Greenlaw’s return. San Francisco plays the Rams in Thursday Night Football next week. “Hopefully, he just keeps getting better,” General Manager John Lynch said ...

The San Francisco 49ers injury issues got a little more clarity on Wednesday, as the team officially ruled out All-Pro left ...

The Los Angeles Rams defeated the 49ers 12-6 and improved to 8-7, while San Francisco falls to 6-8 with the loss. The ...

The San Francisco 49ers are currently in last place in the division and in danger of missing the playoffs. The 49ers have Brock Purdy's contract situation looming in the future and they may have ...

The fantasy football playoffs are here. Which breakout performers from Week 14 are trustworthy and which produced fool's gold that could burn you in the postsea ...

As of Dec. 12 the San Francisco 49ers' odds of winning the Super Bowl, +11000, place them 16th in the league. The 49ers beat the Chicago Bears 38-13 in their most recent outing. Brock Purdy had ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

San Francisco 49ers star left tackle Trent Williams’ newborn son passed away last week, his wife Sondra announced on ...

Claire Kittle, the wife of San Francisco star George Kittle, swapped her snowsuit for a more fitting attire for Sunday's ...

NFL. San Francisco 49ers fans report incident involving a cancer-surviving minor and drunk Buffalo Bills fans NFL. Christian McCaffrey's father devastated after son's serious injury: I feel like ...

49ers. Kyle Shanahan hits rock bottom with the San Francisco 49ers ... featured prominently in WIVB's "Shine Gold" series, which raises funds for children battling cancer. NFL game was supposed ...

The 49ers offense stalled as an entire unit, so it's hard to put the blame for Thursday's anemic offensive output on the rookie. With San Francisco all but mathematically eliminated from playoff ...