Two more deadly waves of the plague hit in the 1500s and 1800s ... In 1798, an British doctor, Edward Jenner, developed a vaccine. In 1966, the World Health Organisation began a global vaccination ...
while the second in the 1500s saw the emergence of a new strain of the disease and the last one at the end of the 1800s spread across Asia. Nuremberg suffered plague outbreaks roughly every 10 ...
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