In drug discovery trials, the potential for a molecule to do harm to an organism must be known accurately. Understanding how a substance under investigation behaves once in the body informs the design ...

Pharmacotherapy with the three Food and Drug Administration (FDA)-approved phosphodiesterase (PDE)5 inhibitors, sildenafil, vardenafil, and tadalafil, is currently the mainstay of treatment for ...

When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens if the dosage ...

Genetically engineered T-cell therapy for HPV-associated epithelial cancers: A first in human, phase I/II clinical trial. CD8 and PD-L1 determination in lung tumor tissue as prognostic biomarker and a ...

Explore our campus, meet lecturers and current students, and learn more about what it's like to study at Manchester. Qualify as a mathematical modeller with key skills in computational approaches in ...

Epirium Bio Presented Positive Phase 1 Safety, Pharmacokinetics and Pharmacodynamics Data for MF-300, Supporting its Role in Muscle Health, as a Late-Breaker at the Gerontological Society of America ...