Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for ...
During the pathogenesis of Parkinson’s disease (PD), α-synuclein pathology may originate in peripheral organs and spread to the CNS. Using human tissue samples and multiple approaches in mouse ...
Over time, the disease can also affect memory and lead to dementia. A similar condition called Lewy Body Dementia (LBD), ...
A novel wireless photothermal DBS nanosystem uses nanoparticles to target and restore damaged neurons in Parkinson’s disease, ...
In a large cohort of patients with autoimmune diseases, treatment with biologic disease-modifying antirheumatic drugs was ...
Blarcamesine potential novel oral treatment to target upstream Alzheimer’s disease pathology through autophagy enhancementImpairment of autophagy ...
Past studies on mice found Lag3 binds to alpha-synuclein proteins and spreads Parkinson's disease pathology in neurons. While deleting Lag3 significantly impedes this process, it does not ...