Stem cells can undergo self-renewing asymmetric cell division to produce two unequal daughters; one enters a programme of differentiation, whereas the other retains stem-cell identity. Using ...

The phosphotyrosine-binding (PTB) domain of Numb, a protein involved in asymmetric cell division, has recently been shown to bind to the adapter protein Lnx through an LDNPAY sequence, to the Numb ...