Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding ...

Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats. However, when the brain is subjected to hyperosmotic stress ...

Microglia, the brain's immune cells, usually serve as diligent guardians ... While some continue to function effectively, others gradually lose their protective role and start secreting small ...

The research revealed that dark microglia produce and release toxic lipids that damage neurons and oligodendrocyte progenitor ...

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Following TBI, microglia — brain-resident macrophages — rapidly migrate to the site of injury, helping to clear damaged cells ... such as impaired motor function and spatial memory.

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

lysosomal function, protein degradation, and lipid metabolism were up. Many of them matched the Mg-2 and Mg-4 subtypes the single-cell RNA sequencing had identified. Plaque-adjacent microglia churned ...