A newly identified metabolite in human feces improves immunotherapy and could radically change the treatment of lung cancer.

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to ...

A total of 235 metabolites are associated with incident T2D, with a signature of 44 metabolites improving prediction of T2D.

The field of colorectal cancer (CRC) research is increasingly focused on understanding how gut microbiota and their metabolites influence therapeutic ...

“Integrating these data in large samples allowed us to identify early metabolic pathway changes that precede type 2 diabetes, providing new insights into disease mechanisms,” said Jun Li, MD, ...

Researchers have discovered how a metabolite involved in repairing damaged DNA not only controls a person’s sensitivity to cancer therapies but can also protect healthy tissues from damage. The ...

Drug metabolism is a central factor in drug discovery and development, impacting safety, pharmacokinetics, and pharmacodynamics. Research into drugs’ in vitro metabolism in human and animal tissues ...

High urine levels of adenine, a metabolite produced in the kidney, were associated with a higher risk of kidney failure in three international research cohorts. Urine levels of adenine, a metabolite ...

Newborns who had an atypical pattern of metabolites were more than 14 times as likely to die of sudden infant death syndrome (SIDS), compared to infants who had more typical metabolic patterns, ...