The research team specifically focused on immune cells called cardiac macrophages. These cells normally help keep heart tissue healthy by sustaining metabolism and clearing out harmful bacteria, but ...

Using animal models, they demonstrated that bone marrow-derived immune cells called macrophages secrete GPNMB, which binds to the receptor GPR39, promoting heart repair. These findings offer a new ...

In the new work, the scientists discovered that when the heart is in a diseased state, the regulatory gene Brd4 is turned on in macrophages, and it makes the immune cells produce IL-1β ...

UCLA scientists have identified the protein GPNMB as a critical regulator in the heart’s healing process after a heart attack ...

It turned out that epigenetic changes in macrophages-;innate immune cells that are among the first responders to a threat-;had developed a kind of "memory" following COVID that allowed these cells ...

Scientists have identified the protein GPNMB as a critical regulator in the heart's healing process after a heart attack. UCLA scientists have identified the protein GPNMB as a critical regulator ...