Lacking an animal model, they were limited to observing its progressive ... Moreover, “Neurotoxin MPTP and the dopaminergic system in Parkinson’s disease” was recently identified as one of the 30 ...
Interestingly, treatment of MPTP-intoxicated mice with nanozyme ... for neuroprotection of dopaminergic neurons in a mouse model of Parkinson's disease.
Figure 1: Lentiviral GDNF delivery is neuroprotective in the monkey Parkinson Disease model. The vector was administered 1 week after the injection of the MPTP toxin; that is, after the monkeys ...
Figure 1: Cyclin-dependent kinase 5 (Cdk5) downregulates peroxiredoxin-2 (Prx2) activity, leading to an accumulation of reactive oxygen species in the MPTP model of Parkinson's disease.
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