The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...

The Ki-67 protein is expressed in all phases of the cell cycle except G0 and serves as a good marker for proliferation. Studies that have evaluated proliferation index by Ki-67 IHC in breast cancer ...

To meet this need, researchers have expanded traditional histological methods, such as immunohistochemistry (IHC), to analyze markers, including proteins and transcripts, in single tissue sections.

The FISH scoring system is automated and, thus, less prone to subjective interpretations than conventional IHC. In addition, the basal expression of HER-2/neu offers an intrinsic control to ...