A type of rare T cell triggers a cascade of signals amplifying inflammation and ultimately leading to liver fibrosis, ...

When the liver is injured - for example, due to bile accumulation - immune cells become activated. In mouse experiments, the ...

A new metabolic mechanism describes how tumors disable “gatekeeper” cells to prevent immune response to cancer.

Several liver transplant recipients have stayed off anti-rejection drugs for at least three years following an experimental ...

UPMC and University of Pittsburgh clinician-scientists have weaned and kept multiple liver transplantation patients off of ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria ...

Dendritic cells (DCs) serve as pivotal sentinels of the immune system, bridging innate and adaptive responses by processing and presenting antigens to T cells. Their inherent versatility enables them ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the Institute for Research in ...

Researchers at the University of Pittsburgh gave transplant recipients certain immune cells from their organ donors. It ...