One can also argue that large DNA viruses arose through a regressive process whereby once-independent entities lost key genes over time and adopted a parasitic replication strategy. Finally ...

Viral reverse transcriptase (RT) plays a critical role in replication (e.g., retroviruses, that reverse transcribe RNA ...

The following is a summary of “Cobalt chloride-mimicked hepatocyte cell hypoxia induces TREX1 leading to Hepatitis B virus ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

The virus remains dormant in most people but can reactivate in those who have received a kidney transplant. As there are currently no treatments for BKPyV, infection can cause graft loss. With only ...

CHAMPAIGN, Ill. (CBS) -- A tiny hand crafted from DNA in a lab in Illinois may be able to help researchers get a hold of viruses and isolate them. Scientists at the University of Illinois Urbana ...

ATP-dependent DNA ligases are also encoded by eukaryotic DNA viruses that conduct some or all of their replication cycle in the cytoplasm. These include vaccinia virus, African swine fever virus, and ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

Human MxA protein suppresses mammalian H5N1 virus replication, but emerging mutations may enable partial evasion, raising ...

are specific nuclear sites used as 'workbenches' to couple viral DNA replication with capsid assembly. Our study of human papillomavirus assembly has been translated into the development of vaccine ...

The six subunit ORC is essential for initiation of DNA replication in eukaryotes. Cancer cell-lines in culture can survive and replicate DNA replication after genetic inactivation of individual ORC ...