The regulation of the cell cycle is a fundamental process ensuring the accurate replication and division of cells. Central to this regulation are the Cdc25 phosphatases, which activate ...

The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, ...

A precision cancer strategy that selectively kills tumour cells while leaving healthy tissue intact may be within reach for ...

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...

Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.