Expansion of antigen-specific T cells (cytomegalovirus) counts for reduced repertoire diversity. B-cell functions are altered with age: antibody production, affinity and isotype switching.

They found that CMV infection triggered genetic pathways that encouraged inflammation, disrupted metabolism and prompted ...

The researchers identified a strong correlation between nervous system cells and human cytomegalovirus. "We're able to apply this cutting-edge technology to the spinal fluid samples, which was able to ...

Swiss pharmaceutical giant Novartis has teamed up with an American biotech company to develop the first commercial vaccine for cytomegalovirus (CMV), which kills or disables tens of thousands of ...

Triplex is designed to induce CMV-specific T cell immunity in donors, which is then transferred to the transplant recipients, potentially reducing the need for antiviral medications post-transplant.

The approval marks the culmination of a lengthy development for a drug that failed a phase 3 trial more than a decade ago for CMV prevention in hematopoietic stem cell transplant (HSCT ...

Natural killer cell deficiency should be considered in patients susceptible to herpes virus or papillomavirus with persistently decreased NK cell function.

HSV and CMV reactivation in critically ill patients suggests a T cell defect, and studies in ICU patients, especially those with sepsis, report extensive loss of CD4 + and CD8 + T cells.