Artificial biosynthetic pathways are typically assembled and optimized progressively, from earlier to later steps. This commentary highlights the potential of an alternate regressive method for ...

Researchers at Ohio State University Medical Center have identified a key enzyme that may be used to combat one of the deadliest types of brain canc ...

Starch and oils are known as storehouses of carbon in plants. However, the way in which carbon resources are allocated during metabolism in plants remained unknown. Now, however, using a forward ...

More information: Xiaojie Chen et al, Research progress on the biosynthesis, metabolic engineering, and pharmacology of ...

Anabolic – this type of pathway requires energy and is used to build up large molecules from smaller ones (biosynthesis). Catabolic – this type of pathway releases energy and is used to break ...

In addition, the researchers designed two auxotrophic yeast strains (met15Δ and ade2Δ) to form a mutualistic relationship, cross-feeding metabolites while dividing the biosynthetic pathway into ...