The following is a summary of “Faulty Gap Filling in Nucleotide Excision Repair Leads to Double-Strand Break Formation in ...

The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.

Cells arrest their cell cycle upon DNA damage through the activation of the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) kinase pathways. In plants, transcriptional ...

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...

Short for ataxia telangiectasia and Rad3-related kinase ... to Tagrisso in the MARIPOSA trial in treatment-naive, EGFR-mutated NSCLC. Join the conversation, on Tuesday 28th January @ 10 am ...