Adenosine is a short-acting endogenous molecule that is a purine nucleoside. The half-life is 6 seconds. Adenosine receptor activation results in multiple different actions depending on the location.

When you drink coffee or other caffeinated beverages, caffeine blocks the receptors in your brain that normally absorb adenosine. Adenosine is a molecule that makes you feel sleepy by slowing nerve ...

Can-Fite BioPharma has secured a US patent for Namodenoson, its lead drug candidate, for use as an anti-obesity treatment.

We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

More than two years after acquiring Tarus Therapeutics, Portage Biotech is relaunching Tarus’ adenosine receptor antagonists in a standalone company helmed by a familiar leader. The offshoot ...

The reaction product is adenosine diphosphate (ADP), and the phosphate group either ends up as orthophosphate (HPO 4) or attached to another molecule (e.g. an alcohol). Even more energy can be ...

The Namodenoson oral drug is well positioned in the field of anti-obesity agents due to its activity and favorable safety profile Ramat Gan, ...

A recent study by researchers at the University of Florence and collaborators has demonstrated the efficacy of MRS-3997, a dual adenosine A2A/A2B receptor agonist, in reducing brain damage and ...

The activation of the adenosine A2A receptor, which is mediated by the inhibition of adenosine A1 receptor, has been associated with depression-like behavior and anhedonia. High levels of cortisol, ...

the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3, 5-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle.