That means Milton could be preparing to make his first appearance in an NFL regular season game. On the Patriots’ list of inactives, there were a total of six players ruled out for the game, including cornerback Christian Gonzalez and tight end Hunter Henry.

For the first time all season, the Patriots have made quarterback Joe Milton active for a game. The sixth-round rookie had previously served exclusively as a third-string emergenc

The Patriots’ leading receiver is inactive vs. the Bills, and the team will make all three quarterbacks active for the first time all season.