Lake Tarpon is a freshwater lake located about 10 miles west of Tampa in Palm Harbor and Tarpon Springs, Florida. Lake Tarpon is the largest freshwater lake in Pinellas County with a surface area of 2,534 acres. Its watershed encompasses 52 square miles. Its two largest tributaries are South Creek and Brooker Creek. The lake is a regional recreational d…Lake Tarpon is a freshwater lake located about 10 miles west of Tampa in Palm Harbor and Tarpon Springs, Florida. Lake Tarpon is the largest freshwater lake in Pinellas County with a surface area of 2,534 acres. Its watershed encompasses 52 square miles. Its two largest tributaries are South Creek and Brooker Creek. The lake is a regional recreational destination and is renowned for its largemouth bass fishing.